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Chemistry Guest Seminars

Organic Seminars 2017

Wednesday, September 27, 2017, 3:30pm - 4:30pm, WEL 2.122

Metalloprotein Catalysts for Selective Group Transfer Reactions

Rudi Fasan

Associate Professor

University of Rochester Dept. of Chemistry

Research Group Web Pagerudi fasan

The research of the Fasan Group focuses on the design, development, and investigation of novel chemo-biosynthetic and chemo-enzymatic strategies for the discovery of biologically active molecules. Through these methodologies, we develop novel chemical agents useful for probing cell signaling pathways and controlling biomolecular interactions implicated in cancer, malaria, and other diseases.  All our projects involve the synergistic integration of rational design, chemical synthesis, protein chemistry, molecular biology, and molecular evolution methods toward the development of enabling molecular discovery platforms of practical and broad utility.


Recent Publications

Author Metrics

h-index:  21   Total Publications:  60   Total Citations:  1334

(Web of Science, August 2017)

 

Distinguished Alumni Lecture

Monday, September 25, 2017, 3:30pm - 4:30pm, WEL 2.122

Nickel-Catalyzed Cross-Electrophile Coupling: Selectivity and Reactivity

Hegui Gong

Professor (PhD, UT Austin, 2005)

Shanghai University, Dept. of Chemistry  hegui gong

Research Group Web Page

Our group has been centered on the development reductive coupling of two different electrophiles which leads to efficient C-C bond formation.  The second research field in our group emphasizes the design of strong H-bonding motif in aqueous media, which can be applied to materials and biological studies.


Recent Publications

Author Metrics

h-index:  16   Total Publications:  36   Total Citations:  1027

(Web of Science, August 2017)

Friday, July 28, 2017, 03:30pm - 04:00pm, WEL 2.122

Next-Generation Responsive, Biological, and Dynamic Materials

Brent Sumerlin

Professor

University of Florida, Dept. of Chemistry

Brent SumerlinResearch Group Web Page:  sumerlin.chem.ufl.edu

ORCID  0000-0001-5749-5444

The Sumerlin Research Group investigates well-defined polymeric materials with selected functionality, composition, and molecular architecture. Our particular focus is on polymers that are water-soluble and stimuli-responsive. Such "smart" polymers have the ability to self-assemble or dissociate in solution in response to changes in their surroundings. Potential target applications include controlled and targeted drug delivery, surface modification, and the synthesis of self-healing materials. Our interests are at the interface of bio-, organic, and polymer chemistry, with particular focus on fusing the fields to prepare materials with synergistic properties.


 

Most Recent Publications:

  1. Eva Blasco, Michael Sims, Anja S. Goldmann, Brent Sumerlin, Christopher Barner-Kowollik “Polymer Functionalization” In revision.

  2. Bryan S. Tucker, McKenzie L. Coughlin, C. Adrian Figg, and Brent S. Sumerlin “Grafting-From Proteins Using Metal-Free PET-RAFT Polymerizations Under Mild Visible-Light Irradiation” ACS Macro Letters 2017, 6, 452-457.  DOI

  3. William L. A. Brooks, Gertjan Vancoillie, Christopher P. Kabb, Richard Hoogenboom, Brent S. Sumerlin “Triply-Responsive Block Copolymers Combining pH-Responsive, Thermoresponsive, and Glucose-Responsive Behaviors” Journal of Polymer Science, Part A: Polymer Chemistry 2017  DOI: 10.1002/pola.28615

  1. C. Adrian Figg, Ashton N. Bartley, Tomohiro Kubo, Bryan S. Tucker, Ronald K. Castellano and Brent S. Sumerlin “Mild and efficient synthesis of ω,ω- heterodifunctionalized polymers and polymer bioconjugates” Polymer Chemistry 2017, 8, 2457-2461.  Link

  2. Xiao Wang, C. Adrian Figg, Xiaoqing Lv, Yongqi Yang, Brent S. Sumerlin, Zesheng An “Star Architecture Promoting Morphological Transitions during Polymerization-Induced Self-Assembly” ACS Macro Letters 2017, 6, 337-342.  DOI

  3. Christopher S. O’Bryan, Tapomoy Bhattacharjee, Samuel Hart, Christopher P. Kabb, Kyle D. Schulze, Indrasena Chilakala, Brent S. Sumerlin, W. Gregory Sawyer, Thomas E. Angelini “Self-Assembled Micro-Organogels for 3D Printing Silicone Structures” Sci. Adv., 2017  Link

  4. Hao Sun, Christopher P. Kabb, Yuqiong Dai, Megan R. Hill, Ion Ghiviriga, Abhijeet P. Bapat and Brent S. Sumerlin “Macromolecular metamorphosis via stimulus- induced transformations of polymer architecture” Nature Chemistry 2017, accepted. DOI:10.1038/nchem.2730.

  5. Jawaher A. Alfurhood, Hao Sun, Christopher P. Kabb, Bryan S. Tucker, James H. Matthews, Hendrik Luesch and Brent S. Sumerlin “Poly(N-(2- hydroxypropyl)methacrylamide)–valproic acid conjugates as block copolymer nanocarriers” Polymer Chemistry 2017DOI 10.1039/C7PY00196G.

  6. R. Nicholas Carmean, C. Adrian Figg, Georg M. Scheutz, Tomohiro Kubo, and Brent S. Sumerlin “Catalyst-Free Photoinduced End-Group Removal of Thiocarbonylthio Functionality” ACS Macro Letters 2017, 6, 185-189.  DOI: 10.1021/acsmacrolett.7b00038

  7. C. Adrian Figg, R. Nicholas Carmean, Kyle C. Bentz, Soma Mukherjee, Daniel A. Savin, and Brent S. Sumerlin "Tuning Hydrophobicity To Program Block Copolymer Assemblies from the Inside Out" Macromolecules 2017, 50, 935-943.   DOI:  10.1021/acs.macromol.6b02754


Author Metrics (Web of Science, July 2017)

h-index:  54   Total Publications:  157    Total Citations:  8,678

 

highly cited   Recent Highly Cited Papers (Web of Science)*

  • Brooks, WLA; Sumerlin, BS.  Synthesis and Applications of Boronic Acid-Containing Polymers: From Materials to Medicine.  Chemical Reviews, 116, 2016, 1375-97. DOI
  • Hill, MR; Carmean, RN; Sumerlin, BS.  Expanding the Scope of RAFT Polymerization: Recent Advances and New Horizons.  Macromolecules, 48, 2015, 5459-69. DOI
  • Cobo, I; Li, M.; Sumerlin, BS.  Smart hybrid materials by conjugation of responsive polymers to biomacromolecules.  Nature Materials, 14, 2015, 143-59.  DOI
  • Figg, CA; et al.  Polymerization-induced thermal self-assembly (PITSA).  Chemical Science, 6, 2015, 1230-36.  DOI
  • Roy, D.; Brooks, WLA; Sumerlin, BS.  New directions in thermoresponsive polymers.  Chemical Society Reviews, 42, 2013, 7214-43.  DOI

* Highly Cited Papers received enough citations to place them in the top 1% of their academic fields based on a highly cited threshold for the field and publication year. 

Google Scholar Metrics


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