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Chemistry Guest Seminars

Organic Seminars 2018

Monday May 7, 3:30 - 5:00pm, WEL 2.122  john bower

Catalytic Chirality Generation: New Strategies for Organic Synthesis

John Bower

Professor of Chemistry

University of Bristol

Research Group Web Page

The group’s research interests lie broadly within the area of asymmetric catalysis with a particular focus on metal-catalysed processes and their application to heterocyclic chemistry. A special emphasis is placed on the development of green processes (i.e. atom economy, step economy and selectivity).

  • asymmetric catalysis
  • heterocyclic chemistry
  • total synthesis
  • mechanism
  • medicinal chemistry

Publications 

Author Metrics

h-index:  29   Total Publications: 61   Total Citations:  2109  (Web of Science, Apr 2018)

Distinguished Alumni Lecture

Friday, May 4, 3:30 - 5:00pm, WEL 2.122  scott grayson

The synthesis and applications of controlled macromolecular architectures: some investigations of cyclic and dendritic polymers

Scott Grayson

Associate Professor

Tulane University

Research Group Web Page

The research in the Grayson group covers a range of fields, from fundamental exploration of polymer architecture, to investigations of their medical or materials applications.  Our research group has developed new synthetic techniques for making high purity cyclic polymers, and have investigated the unique physical properties of these polymers, with respect to exact linear analogs.   These physical studies have largely been carried out through collaboration and have included investigations of degradation, crystallization, size in solution, gas phase conformations, etc. 

Publications 

Author Metrics

h-index:  26   Total Publications: 80   Total Citations:  3743  (Web of Science, Apr 2018)

Mahler Lecture

Wednesday, April 25, 3:30 - 4:30pm, WEL 2.122  itami

Tuning Metallocorroles Properties for Catalyzing Energy- and Medicine-Relevant Processes

Zeev Gross

Professor

Technion - Israel Institute of Technology

Research Group Web Page

The research in our group is focused on the rational design of new corrole complexes for multiple purposes. After tuning their chemical and photophysical properties by selective synthesis protocols that we devise, the corrole derivatives are introduced as key elements for a variety of applications: catalysis, small molecule activation, catalytic oxidation/reduction of water, drug development, and more.  The tools applied by the research group include organic and inorganic synthesis, physical-organic methodologies, advanced spectroscopy, and electrochemistry, as well as biochemical protocols. Our 1999 discovery on the synthesis of what remains the most stable and accessible corrole to date created an enormous flurry of research activity on corrole-chelated metal complexes. This is reflected in the transition from what used to be no more than a scientific curiosity to a highly vibrant field. As of 2017, 150 out of the 180 publications that we have published are on corroles and we hold 7 patents on these molecules and their utility.  On top of fundamental research, we are promoting practical aspects in the fields of asymmetric catalysis, alternative energy, and drug development.

Publications  (Word Doc)

Author Metrics

h-index:  54   Total Publications: 180   Total Citations:  8610  (Web of Science, Mar. 2018)

Highly Cited in Field:  3 papers

Rowland Pettit Centennial Visiting Professorship

Thursday, April 20, 3:30 - 5:00pm, WEL 2.122  itami

Exploring molecular nanocarbon science

Kenichiro Itami

Professor

Nagoya University

Research Group Web Page

Our group has pioneered an increasingly general synthesis platform for a range of functional molecules including molecular nanocarbons, π-conjugated organic materials, pharmaceuticals, and small molecules for plant biology and chronobiology. The uniqueness of our approach can be seen from the fact that most of the game-changing functional molecules that we have created were rapidly synthesized or discovered by our unique and powerful C-H activation catalysts and reactions.  During the last 10 years in Nagoya, the Itami group has focused on addressing some of the grand challenges in the chemistry of arene-assembled molecules. Our endeavors have led to (i) the development of new catalysts for C-H activation/coupling; (ii) the rapid synthesis of pharmaceuticals and natural products; (iii) the discovery of new synthetic bio-molecules particularly for plant biology and chronobiology; (iv) the development of optoelectronic π-materials; and (v) the controlled bottom-up synthesis of nanocarbons such as carbon nanotubes, graphene nanoribbons, and three-dimensional nanocarbons.

Publications

ResearcherID:  B-5110-2011

Author Metrics

h-index:  59   Total Publications: 257   Total Citations:  12,560  (Web of Science, Mar. 2018)

Highly Cited in Field:  20 papers

Monday, April 16, 3:30 - 4:30pm, WEL 2.122  ngai

Development of Novel Chemical Tools for Accessing Unexplored Chemical Space

Ming-Yu Ngai

Assistant Professor

Stony Brook University

Research Group Web Page

PhD, UT Austin, 2008 (Krische)

The Ngai lab focuses on (i) developing novel and practical synthetic methodologies to address unmet challenges in organic synthesis and medicinal chemistry, and (ii) identifying and developing new radiotracers for Positron Emission Tomography (PET) imaging to elucidate disease mechanisms, identify drug targets, assess treatment efficacy, and accelerate drug discovery and development.  Our research programs are multidisciplinary, covering organic and organometallic chemistry, medicinal chemistry, photochemistry, radiochemistry, and biomedical imaging.

Publications

ORCID:  https://orcid.org/0000-0002-3055-6662

Author Metrics

h-index:  13   Total Publications:  22   Total Citations:  1099  (Web of Science, Mar. 2018)

Friday, April 13, 3:30 - 4:30pm, WEL 2.122 nate lynd

N-Al Catalysts for Living Polymerization of Epoxides to Functional Polyethers

Nate Lynd

Assistant Professor

McKetta Dept. of Chemical Engineering, UT Austin

Lynd Polymer Group

We carry out fundamental and applied research in polymer science guided by the principles of simplicity, sustainability, and relevance to key technological challenges in chemical engineering for the 21st century in energy, environment, security, and materials for healthcare. Synthesis is the primary tool that we use to answer fundamental questions, and bring to bear in applied research projects. However, modeling efforts may be used to facilitate materials design, and to provide context for the interpretation of data. Particularly, we are engaged in research efforts that create and utilize new functional and reactive polyether materials and block polymers. Newer work is built on a foundation of novel techniques for advanced copolymer structure determination and detailed mechanistic understanding which facilitate the compositional control of structure-property-processing relationships.


Publications
Publications (Google Scholar)

Author Metrics

h-index:  24   Total Publications:  59   Total Citations:  1734  (Web of Science, Feb. 2018)

h-index:  24  Total Publications:  61  Total Citations: 1764  (Scopus, Feb. 2018)

h-index:  26  Total Citations:  2126 (Google Scholar, Feb. 2018)

Friday, March 16, 3:30 - 4:30pm, WEL 2.122  doron pappo

Mechanistically Driven Catalyst Design for Oxidative Coupling Reactions

Doron Pappo

Associate Professor

Ben-Gurion University of the Negev

Research Group Web Page

Dr. Pappo's research interests are focused on organic synthesis, with particular emphasis on mechanistically driven catalyst design for selective oxidative coupling reactions. 


Publications
Publications (Google Scholar)

Author Metrics

h-index:  12   Total Publications:  29   Total Citations:  548  (Web of Science, Feb. 2018)

h-index:  12  Total Publications:  29  Total Citations:  572  (Scopus, Feb. 2018)

h-index:  14  Total Citations:  640  (Google Scholar Citations, Feb. 2018)

Monday, February 19, 1:00pm - 2:00pm, NHB 1.720  michaelis

Synthetic Applications of Enzyme-Inspired Catalysts

David Michaelis

Assistant Professor of Chemistry

Brigham Young University

Research Group Web Page

  • Polymer-supported nanoparticle catalysts
  • Electrophilic Catalysis with Heterobimetallic Complexes
  • α-Helical Peptide Scaffolds as Modular, Tunable, Enzyme-Like Catalysts for Multistep Synthesis

Research interests include: Organic synthesis, catalysis, natural product total synthesis, inorganic synthesis, polymer chemistry, biocatalysis.


Publications

ORCID:  https://orcid.org/0000-0003-3914-5752

Author Metrics

h-index:  11   Total Publications:  18   Total Citations:  517  (Web of Science, Feb. 2018)

h-index:  11  Total Publications:  19  Total Citations:  536  (Scopus, Feb. 2018)

Vista Lecture

Friday, February 16, 3:30pm - 5:00pm, WEL 2.122  lee cronin

Exploring Transition in Chemical Complexity

Lee Cronin

Professor of Chemistry

University of Glasgow

Research Group Web Page

Research in the Cronin Group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.


Publications

ORCID:  https://orcid.org/0000-0001-8035-5757

Author Metrics

h-index:  59   Total Publications:  324   Total Citations:  14,409  (Web of Science, Jan. 2018)

highly citedHighly Cited:  7 papers

Faculty Recruiting Seminar  David Romney

Wednesday, February 14, 3:30pm - 4:30pm, WEL 2.122

Evolvable Catalysts for Organic Synthesis

David K. Romney

Postdoctoral Researcher, Chemical/Bioengineering

Caltech

F.H. Arnold Group Web Site

PhD, Yale, 2015

Arnold Group:  Enzyme activity; Target-oriented biocatalysis; Protein engineering.


Publications (Google Scholar)

ORCID:  https://orcid.org/0000-0003-0498-7597

Author Metrics

h-index:  8   Total Citations:  182  (Google Scholar Citations, Jan. 2018)

Faculty Recruiting Seminar  amanda cook

Monday, February 12, 3:30pm - 5:00pm, WEL 2.122

Mechanistic Studies of Catalytic Reactions in Solution and on Surfaces: C–H Functionalization and Hydroamination Reactions

Amanda K. Cook-Sneathen

Postdoctoral Fellow, Inorganic Chemistry

ETH Zurich

Copéret Group Web Site

PhD, Michigan, 2015

Copéret Group:  The controlled functionalization of surfaces is essential for defining the properties of materials used in catalysis, imaging, or microelectronics. Our group works on the surface chemistry of oxides, metallic nanoparticles, and hybrid organic-inorganic materials. In particular, the focus of our research is to master the molecular structures and related properties of supported single-site and nanoparticle catalysts. More recently, we have extended these strategies to applications involving imaging (luminescence and nuclear magnetic resonance) and microelectronic devices. Since our research requires detailed molecular understanding of the surface chemistry of materials, we use a combination of spectroscopic methods (IR, UV-Vis, XPS, XAFS, EPR, and solid-state NMR, etc.), computational chemistry (on molecular and periodic systems), and testing the properties of the materials. The overarching goal is to develop catalysts and devices through rational design.


Publications (ResearcherID)

ORCID:  http://orcid.org/0000-0003-3501-8502

Author Metrics

h-index:  6  Total Publications:  7  Total Citations:  252  (ResearcherID, Jan. 2018)

Friday, February 9, 3:30pm - 5:00pm, WEL 2.122  Bo Li

Mighty Chemistry of Bacterial Small Molecules

Bo Li

Assistant Professor of Chemistry

University of North Carolina

Research Group Web Page

Microbial small molecules, also known as secondary metabolites, were well known for their impressive therapeutic properties and diverse medicinal applications. They also serve important biological functions including self-defense and cell-cell signaling for the producing microbes. However, the physiological roles of many secondary metabolites remain poorly understood. Next-generation genome sequencing revealed that microbes harbor many uncharacterized biosynthetic operons, sometimes up to 25% of their genomes, for the biosynthesis of small molecules. It is unclear what molecules these operons make or what their functions are.  Our lab develops genome-mining strategies to identify and characterize new small molecules from microbes. We are particularly interested in microbes that are associated with eukaryotes and their small molecules that are likely involved in microbe-microbe or microbe-host interactions. Our goal is to explore and exploit the biological functions and therapeutic applications of these molecules.


Publications

ORCID:  http://orcid.org/0000-0002-8019-8891

Author Metrics

h-index:  9   Total Publications:  14   Total Citations:  595  (Web of Science, Jan. 2018)

Faculty Recruiting Seminar  zachariah page

Wednesday, Feb. 7, 2:00 - 3:00pm, NHB 1.720

Synthesis of soft materials for energy harvesting and conservation

Zachariah Page

Postdoctoral Researcher

UC Santa Barbara

Dr. Page's Website

Hawker Group Web Site

PhD, Univ. of Massachusetts Amherst, 2015

Zak's research efforts have focused on synthesis and characterization of hydrophilic conjugated polymers, and their integration into organic photovoltaics, as well as the design of novel compounds for organic light emitting diodes, in-situ analysis of photochemical transformations, and 3D printing of  soft materials. Future research will be interdisciplinary in nature, including aspects of synthetic chemistry, materials science, and engineering and will expand upon knowledge gained during past research experiences. Tailored templating and photochemical approaches will be studied to generate well-defined soft materials and composites with interesting (opto)electronic and mechanical properties, with applications spanning bioelectronics, flexible electronics, and additive manufacturing.


Publications

Publications (Google Scholar Citations)

Author Metrics

h-index:  11    Total Citations:  679  (Google Scholar Citations. Feb. 2018)

h-index:  12  Total Publications:  34  Total Citations:  602 (Web of Science, Feb. 2018)

highly cited paperWeb of Science Highly Cited Paper:  Page, ZA et al.  Fulleropyrrolidine interlayers: tailoring electrodes to raise organic solar cell efficiency.  Science, 346(6208), 2014, 441-444.  DOI:  10.1126/science.1255826

Faculty Recruiting Seminar  Alison Wendlandt

Wednesday, January 31, 3:30pm - 4:30pm, WEL 2.122

Mechanism-guided development of new, selective catalytic reactions

Alison Wendlandt

Postdoctoral Fellow, Chemistry & Chemical Biology

Harvard University

Eric Jacobsen Lab Research Web Page

PhD, Wisconsin, 2015

Jacobsen Lab:  Our program is dedicated to the discovery of practical catalytic reactions, and to the application of state-of-the art mechanistic and computational techniques to the analysis of those reactions. Over the past several years, we have sought and identified new classes of chiral catalysts, and several of these have found widespread application in industry and academia. These include metal-salen complexes for asymmetric epoxidation, conjugate additions, and hydrolytic kinetic resolution of epoxides; copper-diimine complexes for asymmetric aziridination; chromium-Schiff base complexes for a wide range of enantioselective pericyclic reactions; and organic hydrogen bond-donor catalysts for activation of neutral and cationic electrophiles. Our mechanistic analyses of these catalytic systems have helped uncover general principles for future catalyst design, including electronic tuning of enantioselectivity, cooperative homo- and hetero-bimetallic catalysis, hydrogen-bond donor asymmetric catalysis, and anion binding catalysis.


 ResearchGate

Publications (Jacobsen Group)

Author Metrics

h-index:  6  Total Publications:  6  Total Citations:  1044  (Web of Science, Dec. 2017)

highly citedHighly Cited Publication:  Wendlandt, AE; Suess, AM; Stahl, SS.  Copper-catalyzed aerobic C-H functionalizations: trends and mechanistic insights.  Angew. Chem. Int. Ed. 50(47), 2011, 11062-11087.  DOI:  10.1002/anie.201103945

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