Wednesday, September 27, 2017, 3:30pm - 4:30pm, WEL 2.122
University of Rochester Dept. of Chemistry
The research of the Fasan Group focuses on the design, development, and investigation of novel chemo-biosynthetic and chemo-enzymatic strategies for the discovery of biologically active molecules. Through these methodologies, we develop novel chemical agents useful for probing cell signaling pathways and controlling biomolecular interactions implicated in cancer, malaria, and other diseases. All our projects involve the synergistic integration of rational design, chemical synthesis, protein chemistry, molecular biology, and molecular evolution methods toward the development of enabling molecular discovery platforms of practical and broad utility.
(Web of Science, August 2017)
Distinguished Alumni Lecture
Monday, September 25, 2017, 3:30pm - 4:30pm, WEL 2.122
Professor (PhD, UT Austin, 2005)
Our group has been centered on the development reductive coupling of two different electrophiles which leads to efficient C-C bond formation. The second research field in our group emphasizes the design of strong H-bonding motif in aqueous media, which can be applied to materials and biological studies.
(Web of Science, August 2017)
Friday, July 28, 2017, 03:30pm - 04:00pm, WEL 2.122
University of Florida, Dept. of Chemistry
Research Group Web Page: sumerlin.chem.ufl.edu
The Sumerlin Research Group investigates well-defined polymeric materials with selected functionality, composition, and molecular architecture. Our particular focus is on polymers that are water-soluble and stimuli-responsive. Such "smart" polymers have the ability to self-assemble or dissociate in solution in response to changes in their surroundings. Potential target applications include controlled and targeted drug delivery, surface modification, and the synthesis of self-healing materials. Our interests are at the interface of bio-, organic, and polymer chemistry, with particular focus on fusing the fields to prepare materials with synergistic properties.
Eva Blasco, Michael Sims, Anja S. Goldmann, Brent Sumerlin, Christopher Barner-Kowollik “Polymer Functionalization” In revision.
Bryan S. Tucker, McKenzie L. Coughlin, C. Adrian Figg, and Brent S. Sumerlin “Grafting-From Proteins Using Metal-Free PET-RAFT Polymerizations Under Mild Visible-Light Irradiation” ACS Macro Letters 2017, 6, 452-457. DOI
William L. A. Brooks, Gertjan Vancoillie, Christopher P. Kabb, Richard Hoogenboom, Brent S. Sumerlin “Triply-Responsive Block Copolymers Combining pH-Responsive, Thermoresponsive, and Glucose-Responsive Behaviors” Journal of Polymer Science, Part A: Polymer Chemistry 2017 DOI: 10.1002/pola.28615
C. Adrian Figg, Ashton N. Bartley, Tomohiro Kubo, Bryan S. Tucker, Ronald K. Castellano and Brent S. Sumerlin “Mild and efficient synthesis of ω,ω- heterodifunctionalized polymers and polymer bioconjugates” Polymer Chemistry 2017, 8, 2457-2461. Link
Xiao Wang, C. Adrian Figg, Xiaoqing Lv, Yongqi Yang, Brent S. Sumerlin, Zesheng An “Star Architecture Promoting Morphological Transitions during Polymerization-Induced Self-Assembly” ACS Macro Letters 2017, 6, 337-342. DOI
Christopher S. O’Bryan, Tapomoy Bhattacharjee, Samuel Hart, Christopher P. Kabb, Kyle D. Schulze, Indrasena Chilakala, Brent S. Sumerlin, W. Gregory Sawyer, Thomas E. Angelini “Self-Assembled Micro-Organogels for 3D Printing Silicone Structures” Sci. Adv., 2017 Link
Hao Sun, Christopher P. Kabb, Yuqiong Dai, Megan R. Hill, Ion Ghiviriga, Abhijeet P. Bapat and Brent S. Sumerlin “Macromolecular metamorphosis via stimulus- induced transformations of polymer architecture” Nature Chemistry 2017, accepted. DOI:10.1038/nchem.2730.
Jawaher A. Alfurhood, Hao Sun, Christopher P. Kabb, Bryan S. Tucker, James H. Matthews, Hendrik Luesch and Brent S. Sumerlin “Poly(N-(2- hydroxypropyl)methacrylamide)–valproic acid conjugates as block copolymer nanocarriers” Polymer Chemistry 2017, DOI 10.1039/C7PY00196G.
R. Nicholas Carmean, C. Adrian Figg, Georg M. Scheutz, Tomohiro Kubo, and Brent S. Sumerlin “Catalyst-Free Photoinduced End-Group Removal of Thiocarbonylthio Functionality” ACS Macro Letters 2017, 6, 185-189. DOI: 10.1021/acsmacrolett.7b00038
C. Adrian Figg, R. Nicholas Carmean, Kyle C. Bentz, Soma Mukherjee, Daniel A. Savin, and Brent S. Sumerlin "Tuning Hydrophobicity To Program Block Copolymer Assemblies from the Inside Out" Macromolecules 2017, 50, 935-943. DOI: 10.1021/acs.macromol.6b02754
* Highly Cited Papers received enough citations to place them in the top 1% of their academic fields based on a highly cited threshold for the field and publication year.
This work is licensed under a Creative Commons Attribution-NonCommercial 2.0 Generic License.